Macro of a switched-on LED behind its lens: deep red light with a bright centre.

Research

What research shows

Red and near-infrared light has been studied for decades: in laboratories, in sport and in healthcare. Below are the most important studies per topic, with what was studied and what the researchers found.

How we present research

Each study shows what kind of research it is, what was studied and what the researchers found. An overview of dozens of studies gives a broader picture than a single study, and research in people says more than research on cells.

The studies were not carried out with RedLab panels. Much of the research used lasers or medical devices. The outcomes are therefore not a promise for our product.

LEDs and lasers work through the same mechanism

Review · 2018 · Photochemical & Photobiological Sciences · Heiskanen & Hamblin

Much of the research into red light was done with lasers. This review puts research on lasers and LEDs side by side and concludes that LEDs can have the same effect: the property that sets lasers apart, coherence, is not needed for it. LEDs are also suitable for home use and light a large area at once.

Skin and collagen

Within wellness, skin is the most studied area. Studies by different research groups measure smoother skin, fewer wrinkles and more collagen, established with ultrasound and skin biopsies.

Collagen measured with ultrasound

Controlled study · 2014 · Photomedicine and Laser Surgery · Wunsch & Matuschka

136 participants received 30 sessions, twice a week, with red light (611–650 nm) or broadband light. Compared with the control group, skin became smoother and collagen density increased, measured with ultrasound. Participants were also more positive about how their skin looked and felt. Red light alone worked as well as broadband light.

Red and near-infrared for skin ageing, tested double-blind

Randomised, double-blind study · 2007 · Journal of Photochemistry and Photobiology B · Lee et al.

76 participants received light at 830 nm, 633 nm, a combination of both, or a placebo, twice a week for four weeks. Wrinkles decreased by up to 36% and skin elasticity rose by up to 19%. Skin biopsies contained more collagen and elastic fibres. No side effects were reported.

Less wrinkle volume around the eyes with red and amber light

Randomised study · 2023 · Photobiomodulation, Photomedicine, and Laser Surgery · Mota et al.

137 women aged 40 to 65 received ten sessions in four weeks: red light (660 nm) on one half of the face and amber light (590 nm) on the other. Wrinkle volume around the eyes decreased by 31.6% with red and by 29.9% with amber light, at a dose of 3.8 J/cm².

Improvements that lasted after stopping

Study · 2023 · Skin Research and Technology · Couturaud et al.

Researchers followed the effects of red light on signs of skin ageing, including after the sessions had ended. The improvements lasted up to a month after stopping.

More procollagen, less breakdown

Lab research with clinical comparison · 2009 · Journal of Investigative Dermatology · Barolet et al.

In a cultured skin model, pulsed 660 nm light increased production of procollagen, the precursor of collagen, by 31%. An enzyme that breaks down collagen decreased by 18%. The researchers compared this with a clinical study in people.

Yellow light for skin ageing

Randomised study · 2025 · Lasers in Medical Science

30 participants received yellow light at 570 or 590 nm, combined with red and infrared light. Both groups improved on pores, wrinkles, skin texture and pigment spots.

Amber light for skin ageing

Clinical study without a control group · 2004 · Weiss et al.

93 people with different skin types received pulsed amber light at 590 nm. In 90%, signs of skin ageing improved, such as fine lines around the eyes, skin texture, redness and pigmentation.

Caveat: there was no control group, so this is an indication rather than firm evidence. The device also used a special pulse pattern.

830 nm after skin treatments

Review article · 2015 · Laser Therapy · Calderhead et al.

This review article brings together clinical research on 830 nm LEDs immediately after aesthetic treatments. Redness, swelling and bruising subsided more quickly, and the skin recovered faster.

Caveat: this is a summary of earlier research, not a study of its own. The research took place in clinics, after treatments.

Training and recovery

Many studies and several overviews have been done here. They mainly show an effect on endurance, fatigue and recovery. In most studies the light was applied before exercise.

Whole-body light for training and recovery

Systematic review · 2025 · Lasers in Medical Science · Álvarez-Martínez & Borden

This review brings together research on whole-body light therapy around exercise and recovery. Of all sources on this page, it comes closest to using a panel.

More endurance

Systematic review and meta-analysis · 2022 · Sports Medicine · Dutra et al.

An overview of 37 studies with 586 participants. Light improved muscular endurance and time to exhaustion on the bike. The effect was in endurance, not in maximal strength or sprinting.

Better performance with light before exercise

Systematic review and meta-analysis · 2015 · Lasers in Medical Science · Leal-Junior et al.

An overview of 13 good-quality randomised studies. In 12 of them the light was applied before exercise, and 10 found significantly better performance.

Light and muscle tissue: 46 studies in a row

Review · 2016 · Journal of Biophotonics · Ferraresi, Huang & Hamblin

An overview of 46 studies with 1045 participants, using red light, near-infrared and combinations. According to the authors, light can increase the gain in muscle mass after training and lower inflammatory markers and oxidative stress. They even ask whether it should be allowed in competitive sport.

Better muscle performance and less fatigue

Systematic review and meta-analysis · 2018 · Lasers in Medical Science · Vanin et al.

An overview of 39 studies with 861 healthy participants on muscle performance and fatigue during exercise. The outcomes favoured light.

Red light and sleep in athletes

Controlled study · 2012 · Journal of Athletic Training · Zhao et al.

20 elite female basketball players received 30 minutes of whole-body red light at 658 nm every evening for 14 days. Compared with a group receiving no light, they slept better, had more melatonin in their blood and performed better on an endurance running test.

Caveat: a small group, and the comparison group received no sham treatment but no light at all.

810 nm in football players

Randomised, double-blind study · 2016 · Photomedicine and Laser Surgery · Vanin et al.

28 high-level football players received 810 nm light on their thigh before an intense leg exercise, at three doses or placebo. At the highest dose, their muscle strength recovered better, and blood markers of muscle damage and inflammation were lower. There was no effect on muscle soreness.

Caveat: a laser was used, aimed at a single muscle group, and the middle dose showed no effect.

Red + near-infrared and muscle fatigue

Double-blind, placebo-controlled study · 2010 · Photomedicine and Laser Surgery · Baroni et al.

In a double-blind study, 17 healthy, active men received combined LED light at 660 and 850 nm on their thigh muscles, or placebo. After a fatiguing exercise, they retained more strength with light than with placebo.

Caveat: a small group, and the two wavelengths were given together.

940 nm before intense training

Randomised, placebo-controlled study · 2022 · Padoin et al.

28 healthy men received LED light at 630 nm, 940 nm or placebo before intense jump training. After 940 nm, a blood marker of muscle damage was lower after three days than with placebo, and after two days they scored better on a jump test.

Caveat: a small group, and researchers found differences only in certain measurements and at certain times.

Light in healthcare

A large share of research into red and near-infrared light takes place in healthcare. It concerns medical applications, studied with lasers and medical devices and applied by healthcare professionals. We show it because it shows how seriously light is researched. RedLab is a wellness product, not a medical device, and is not intended for these applications. If you have symptoms, see your GP.

940 nm in dentistry

Randomised studies · 2022 · BMC Oral Health · Momeni et al., Morshedzadeh et al.

Research into 940 nm mainly takes place in dentistry, with lasers. After wisdom tooth extraction it gave less pain, and after gum surgery the wound closed faster.

Read the studies: 1 →2 →

Muscles, joints and tendons

Laser therapy for neck pain

Systematic review and meta-analysis · 2009 · The Lancet · Chow et al.

An overview of 16 randomised studies with 820 patients with neck pain, treated with lasers by practitioners. In acute neck pain the chance of improvement was 1.69 times that of placebo, in chronic neck pain 4.05 times. Side effects were mild and similar to placebo.

Laser therapy for knee osteoarthritis

Systematic review and meta-analysis · 2019 · BMJ Open · Stausholm et al.

An overview of 22 studies with 1063 patients, treated with lasers. Pain fell by 14 points on a 100-point scale, and by 19 points at the recommended doses.

Laser therapy for tendon complaints and heel spurs

Systematic review and meta-analysis · 2022 · BMJ Open · Naterstad et al.

An overview of randomised studies with lasers for tendon complaints in the leg and heel spurs. Pain fell by about 13 points on a 100-point scale, and the effect was still present after 4 to 12 weeks.

Support during cancer treatment

Included in an international guideline

Systematic review and clinical guideline · 2019 · Supportive Care in Cancer · Zadik et al. (MASCC/ISOO)

The international MASCC/ISOO guideline recommends light therapy to prevent inflammation of the oral mucosa, a painful side effect of radiotherapy and stem cell transplantation. The light is applied inside the mouth by healthcare professionals. It is the strongest recognition of light therapy in mainstream care.

Fewer severe side effects in the mouth

Systematic review and meta-analysis · 2014 · PLoS One · Oberoi et al.

An overview of 18 randomised studies with 1144 patients. The risk of severe inflammation of the oral mucosa was 63% lower, the risk of severe pain 74% lower.

Skin

Home LEDs for acne

Systematic review and meta-analysis · 2025 · JAMA Dermatology · Ershadi & Barbieri

An overview of 6 randomised studies with 216 participants on home-use LED devices for acne. Compared with control, inflamed spots decreased 45% more. Red light, blue light and the combination all worked.

Hair

Red light for hereditary hair loss

Randomised, double-blind study · 2013 · Lasers in Surgery and Medicine · Lanzafame et al.

44 men wore a helmet with 655 nm red light every other day for 16 weeks, directly on the scalp. Compared with placebo, 35% more hair grew.

Mood

Light for depression

Randomised study · 2018 · Photomedicine and Laser Surgery · Cassano et al. (ELATED-2)

In this study near-infrared light was aimed at the forehead. The study found a positive effect.

New research directions

Topics where the first studies have been done.

Thinking in healthy adults

Systematic review and meta-analysis · 2019 · Photobiomodulation, Photomedicine, and Laser Surgery · Salehpour et al.

This review brought together studies on light to the head in young, healthy adults, and found an improvement in cognitive performance.

Blood sugar after one session

Randomised study · 2024 · Journal of Biophotonics · Powner & Jeffery

30 healthy adults received 15 minutes of 670 nm light on the back, 45 minutes before a sugar drink. The rise in their blood sugar was 27.7% lower than in the group without light. If you have diabetes, do not change anything in your treatment based on this research.

A theory about water in your cells

Lab research · 2015 · Scientific Reports · Sommer et al.

According to this theory, near-infrared light makes the water around ATP synthase, the enzyme that produces energy in your cells, less viscous, so that it could work faster.

How light works

The background to the studies above: how red and near-infrared light works in your body according to researchers. This part is mainly based on research on cells and animals.

In your cells

Why these wavelengths in particular

Lab research · 2004 · Photochemical & Photobiological Sciences · Karu et al.

Cells do not respond equally strongly to every wavelength. The effects peak around 620, 680, 760 and 820 nm, and that pattern resembles the way cytochrome c oxidase absorbs light, an enzyme in your mitochondria. It is the most widely accepted explanation of how red light works.

Light releases a brake on energy production

Review · 2016 · IEEE Journal of Selected Topics in Quantum Electronics · de Freitas & Hamblin

Nitric oxide can bind to cytochrome c oxidase and so slow energy production in the cell. According to the main hypothesis, light releases that nitric oxide, so the cell makes more ATP again.

From light to cell nucleus

Review · 2017 · AIMS Biophysics · Hamblin

Abstract illustration of a cell with a mitochondrion, cell nucleus and red light accents.

Light is absorbed by cytochrome c oxidase and by calcium channels. This is followed by more ATP, a brief signal of reactive oxygen molecules, released nitric oxide and a change in calcium. Those signals switch on controls in the cell that determine which proteins the cell makes.

Not heat, but a light reaction

Review · 2011 · Dose-Response · Huang, Sharma, Carroll & Hamblin

Red light does not work through heat, like a heat lamp. The light is absorbed and starts a chemical reaction: it acts as a signal for the cell.

A second light pathway

Review · 2018 · Photochemistry and Photobiology · Hamblin

Besides the mitochondria, ion channels in the cell membrane also respond to light. The author describes that light gives cells signals similar to training, and therefore calls it a possible ‘exercise mimetic’.

Nitric oxide measured from human skin

Study · 2024 · Journal of Photochemistry and Photobiology · Barolet et al.

18 healthy participants received 15 minutes of light at 455, 660 or 850 nm on the forearm. Then the amount of nitric oxide released from the skin was measured. It was measurable, with clear differences per wavelength. Nitric oxide helps blood vessels relax.

Blood flow with 830 nm

Study in healthy adults · 2020 · Gavish et al.

20 healthy adults received 5 minutes of light on their wrist: near-infrared at 830 nm or red light at 633 nm. At 830 nm, blood flow in the hand increased and continued to rise for another 20 minutes after the session. This did not happen with red light.

Caveat: not everyone responded equally strongly, and the effect was measured shortly after the session.

How deep it goes

Below 600 nm, blood and skin pigment block most light. Above about 1200 nm, water absorbs it. In between lies the optical window, in which light travels through tissue most easily. Around 810 nm, light reaches deepest.

The optical window

Review · 2022 · Frontiers in Photonics

This review of the effects of LEDs on cells explains why red and near-infrared light penetrates deeper than blue or green light.

Measured penetration through tissue

Review · 2019 · Photobiomodulation, Photomedicine, and Laser Surgery · Salehpour et al.

An overview of measurements of how far visible and near-infrared light penetrates tissue, in animals and humans.

Why more is not better

The inverted U

Review · 2009 · Dose-Response · Huang, Chen, Carroll & Hamblin

A low dose of light often works better than a high one. It underlies the principle that more light is not automatically better.

The dose matters

Randomised study · 2015 · Lasers in Medical Science · Ferraresi et al.

Volleyball players received LED light before official matches. At a higher dose, the rise in creatine kinase, a marker of muscle damage, did not occur. With placebo and at a lower dose it did.

How to translate this to your own session is explained under Use and dosing →

Safety and interpretation

These publications are independent research and were not conducted with RedLab products. Their findings are not measured product performance and not a promise of results.

RedLab panels are intended for a light and wellbeing routine, not for diagnosis, treatment or cure. Follow the product instructions and the eye-protection advice. If you have health questions, use medication that increases light sensitivity, or are unsure whether use is suitable, consult a qualified healthcare professional first.